pentobarbital will lessen the extent or outcome of bexarotene by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will decrease the level or impact of tamoxifen by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.pentobarbital increases toxicity of buprenorphine, extended-actin